Research Support

RESEARCH SUPPORT (NON-GOVERNMENTAL):

 
Funding Agency: Scoliosis Research Society, Rosemont, IL
   
Period: January 1988 - January 1989
   
Grant Title: The influence of spinal cord distraction and spinal cord ischemia on somatosensory and neurogenic motor evoked potentials in pigs
   
Investigators: Jeffrey Owen, Ph.D.
  Keith H. Bridwell, M.D.
   
Annual Direct Costs: $24,130. Funded in full
   
Funding Agency: Scoliosis Research Society, Rosemont, IL
   
Period: January 1990 - January 1991
   
Grant Title: The effect of compression and lesioning of cervical and lumbar nerve roots on antidromic sensory and dermatomal evoked potential in animals
   
Investigators: Jeffrey Owen, Ph.D.
  Keith H. Bridwell, M.D.
   
Annual Direct Costs: $34,458. Funded in full
   
Funding Agency: AcroMed - North American Spine Society, Rosemont, IL
   
Period: January 1994 - January 1995
   
Grant Title: The role of transforming growth factor-beta in the spinal cord response to acute spinal trauma
   
Investigators: Michael E. Joyce, M.D.
  Michael F. O'Brien, M.D.
  Lawrence G. Lenke, M.D.
  Keith H. Bridwell, M.D.
   
Annual Direct Costs: $12,500. Funded in full
   
Funding Agency: Sofamor Danek USA, Memphis, TN
   
Period: August 1996 - August 1997
   
Grant Title: Retrospective and prospective surgical spinal database (~4,000 entries)
   
Investigators: Keith H. Bridwell, M.D.
  Lawrence G. Lenke, M.D.
  K. Daniel Riew, M.D.
   
Annual Direct Costs: $10,000. Funded in full
   
Funding Agency: BJC Health System - Innovations in Healthcare Program, St. Louis, MO
   
Period: December 1996 - December 1998
   
Grant Title: Selective nerve root corticosteroid injection: Can its use obviate the need for surgery in patients with lumbar radicular pain?
   
Investigators: K. Daniel Riew, M.D.
  Yuming Yin, M.D.
  Lou Gilula, M.D.
  Lawrence G. Lenke, M.D.
  Keith H. Bridwell, M.D.
   
Total Direct Costs: $19,350. Funded in full; payable over two years
   
Funding Agency: Sofamor Danek USA, Memphis, TN
   
Period: June 1, 1997 - June 1, 1999 (extended to June 1, 2001)
   
Grant Title: Biomechanics of spinopelvic fixation in a human cadaveric model of isthmic spondylolisthesis.
   
Investigators: Keith H. Bridwell, M.D.
  Stephen J. Lewis, M.D.
  John Long, D.V.M.
  Bryan W. Cunningham, M.Sc.
  Douglas Linville, M.D.
  Ravishankar Vedantam, M.D.
  Lawrence G. Lenke, M.D.
   
Annual Direct Costs: $50,556 - first year; $35,000 - second year
   
Funding Agency: DePuy-Motech, Inc., Warsaw, IN
   
Period: February 1, 1997 - February 1, 1999
   
Grant Title: Structural and performance changes in adolescent idiopathic scoliosis patients undergoing anterior vs. posterior thoracic spinal fusion.
   
Investigators: Lawrence G. Lenke, M.D.
  Jack R. Engsberg, Ph.D.
  James Kemp, M.D.
  Marilyn Siegal, M.D.
  Keith H. Bridwell, M.D.
   
Total Direct Costs: $84,000. Funded in full; payable over two years
   
Funding Agency: Ortho Biotech, Inc., Raritan, NJ
   
Period: July 1, 1998 - December 1, 1999
   
Grant Title: An open-label, randomized, parallel-group study comparing the perioperative administration of Procrit (Epoetin Alfa) to the standard of care in blood conservation for idiopathic pediatric/adolescent scoliosis and adult spinal deformity surgeries.
   
Investigators: Keith H. Bridwell, M.D.
  Lawrence G. Lenke, M.D.
  Terri G. Monk, M.D.
   
Total Direct Costs: $60,000. Funded in full; payable over 18 months
   
Funding Agency: Sofamor Danek USA, Memphis, TN
   
Period: August 1, 1998 - August 1, 2000
   
Grant Title: Structural and performance changes in adolescent idiopathic scoliosis in patients fused into the mid and lower lumbar spine.
   
Investigators: Lawrence G. Lenke, M.D.
  Jack R. Engsberg, Ph.D.
   
Co-Investigators: James S. Kemp, M.D.
  Keith H. Bridwell, M.D.
  George S. Bassett, M.D.
   
Total Direct Costs: $75,000. Funded in full; payable over 2 years
   
Funding Agency: Scoliosis Research Society, Rosemont, IL
   
Period: October 1, 1998 - September 1, 2001
   
Grant Title: Comparison of outcome measures in adult scoliosis patients undergoing an extended spinal fusion to L5 or sacrum or revision of previous long spinal deformity fusion surgery.
   
Investigators: Jack R. Engsberg, Ph.D.
  Keith H. Bridwell, M.D.
   
Co-Investigators: Scott D. Minor, Ph.D.
  Lawrence G. Lenke, M.D.
   
Total Direct Costs: $80,308. Funded in full; payable over 3 years
   
Funding Agency: Medtronic Sofamor Danek, Memphis, TN
   
Period: March 1, 2001 - February 28, 2005
   
Grant Title: Washington University Spine Research Center (not-for-profit research center funded by private industry for Washington University/Orthopaedic Surgery spine attendings to conduct clinical research, both retrospectively and prospectively).
   
Investigators: Keith H. Bridwell, M.D.
  Lawrence G. Lenke, M.D.
  K. Daniel Riew, M.D.
   
Total Direct Costs: $1,494,604. Funded in full; payable over 4 years
   
Funding Agency: Medtronic Sofamor Danek, Memphis, TN
   
Period: March 1, 2005 - February 28, 2010
   
Grant Title: Washington University Spine Research Center (not-for-profit research center funded by private industry for Washington University/Orthopaedic Surgery spine attendings to conduct clinical research, both retrospectively and prospectively).
   
Investigators: Keith H. Bridwell, MD
  Lawrence G. Lenke, MD
  K. Daniel Riew, MD
   
Total Direct Costs: $1,948,615. Funded in full; payable over 5 years
   
   

RESEARCH SUPPORT (GOVERNMENTAL):

 
Funding Agency: National Institutes of Health
   
Period: May 31, 2004 - May 31, 2005
   
Grant Title: Spine patient outcomes research trials (SPORT)
   
Principal Investigator: Lawrence G. Lenke, M.D.
   
Co-Investigators: Keith H. Bridwell, M.D.
  K. Daniel Riew, M.D.
  Ralph G. Dacey, Jr., M.D.
  Carl Lauryssen, M.D.
  Anthony Margherita, M.D.
  Heidi Prather, D.O.
   
Total Direct Costs: $503,252 (part of a $13,546,017 grant). Funded in full; payable over 5 years